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University of Iowa News Release

 

April 21, 2011

UI cancer researcher teams to receive Oberley Seed Grants

Six teams of researchers at Holden Comprehensive Cancer Center at the University of Iowa, including faculty from three UI colleges, have received 2011 Oberley Seed Grant Program awards.

The two-year, $50,000 grants provide support for new interdisciplinary and collaborative projects that are likely to lead to externally supported cancer research funding. The seed grant program memorializes former UI faculty member Larry Oberley, Ph.D., a leader in free radical and cancer biology who passed away in spring 2008. The projects include:

--Hai-Hui Xue, M.D., Ph.D., assistant professor of microbiology, will evaluate whether a protein complex known as GABP α2β2 tetramer can be used as a target for treatment of leukemia.

--David Roman, Ph.D., assistant professor of medicinal and natural products chemistry in the College of Pharmacy, will work with Michael Henry, Ph.D., and Michael Cohen, M.D., to study approaches for targeting RGS17, a protein that may contribute to prostate cancer.

--Melissa Lai Tee Teoh, Ph.D., assistant research scientist and adjunct assistant professor of radiation oncology, will work with Ryan Askeland, M.D., Ronald Weigel, M.D., Ph.D., James Howe, M.D., and Brian Smith, Ph.D., to investigate the genetics of an enzyme called EcSOD that might be useful in predicting breast cancer development.

--John Sunderland, Ph.D., associate professor of radiology and colleagues will work with Siegfried Janz, M.D., to study whether novel approaches to PET imaging can measure tumor shrinkage in experimental models of cancer.

--Elaine Smith, Ph.D., professor of epidemiology in the College of Public Health and professor of obstetrics and gynecology with UI Health Care, will work with Michael Goodheart, M.D., Doug Spitz, Ph.D., Rick Domann, Ph.D., and Linda Rubenstein, Ph.D., to study the association between oxidative stress and risk of endometrial cancer.

--Robert Cornell, Ph.D., associate professor of anatomy and cell biology, will work with Ron Weigel, M.D., and Mohammed Milhem, M.D., to study the role of transcription factor activator protein 2 that may contribute to the resistance of melanoma to chemotherapy.

STORY SOURCE: University of Iowa Health Care Media Relations, 200 Hawkins Drive, Room W319 GH, Iowa City, Iowa 52242-1009

MEDIA CONTACT: Jennifer Brown, 319-356-7124, jennifer-l-brown@uiowa.edu