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University of Iowa News Release


July 2, 2008

Sigmund named to Carver Chair in Hypertension Research

Curt D. Sigmund, Ph.D., professor of internal medicine and molecular physiology and biophysics in the UI Roy J. and Lucille A. Carver College of Medicine, has been named to the Roy J. Carver Chair in Hypertension Research. The five-year appointment was effective July 1.

The endowed chair was established through gifts to the UI Foundation by the Roy J. Carver Charitable Trust of Muscatine, Iowa, to support research in cardiovascular medicine at the UI.

Sigmund is internationally known for his research examining the genetic basis of hypertension, renal and neural mechanisms causing hypertension, and the regulation of blood vessel function. A recent study in Cell Metabolism, which identified a molecular pathway in blood vessels that controls blood pressure and vascular function, exemplifies his team's use of state-of-the-art genetic manipulation to understand fundamental mechanisms regulating blood pressure.

A UI faculty member in internal medicine (cardiology division) and molecular physiology and biophysics since 1991, Sigmund leads the Roy J. Carver Program of Research Excellence in the Functional Genomics of Cardiovascular Disease and the UI Center for Functional Genomics of Hypertension, which is currently funded with a five-year, $10 million grant from the National Institutes of Health. He also is director of the UI Transgenic Animal Facility.

"Dr. Sigmund's appointment to the Carver Chair in Hypertension Research is fitting recognition of his international prominence in the field of cardiovascular research and of his outstanding academic achievements and contributions to the Carver College," said Jeffrey Field, M.D., professor and interim head of internal medicine. "The significant advances that Dr. Sigmund has made in understanding the molecular and physiological basis of hypertension will have important clinical implications for the many patients affected by hypertension and its complications."

Sigmund received a master's degree in biology in 1984 and a doctorate in molecular and cellular biology in 1987 at the State University of New York at Buffalo. He served as a research affiliate from 1987-88, and as a postdoctoral fellow from 1988-1991, at the Roswell Park Cancer Institute in Buffalo, N.Y.

The UI acknowledges the UI Foundation as the preferred channel for private contributions that benefit all areas of the university. For more information, visit the UI Foundation's Web site at

STORY SOURCE: University of Iowa Health Science Relations, 5137 Westlawn, Iowa City, Iowa 5224-1178

MEDIA CONTACT: Becky Soglin, 319 335-6660