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University of Iowa Health Care News Release

May 17, 2004

UI Heart Disease Prevention Study Invites Participants

People ages 55 or older who have had a heart attack or episode of chest pain within the past year are invited to participate in a University of Iowa Health Care study on heart disease prevention. Those who also have diabetes may be 18 years or older to participate. The study will investigate whether long-term use of an investigational medication, compared to placebo (inactive pill), will help reduce the risk of future heart disease events.

The study will last two years and involve 12 visits to UI Hospitals and Clinics at approximately three-month intervals. Eligible participants randomly will be assigned to take either the study drug or the placebo. The study drug is thought to be an antioxidant that reduces inflammation associated with fatty build-up in the arteries (atherosclerosis).

In addition to taking the study drug or placebo, all participants will continue on their current standard treatment for their heart disease during the two-year study. The study visits will involve, at no cost to participants, physical exams, electrocardiograms, blood and laboratory evaluations, and study medication. Compensation for travel and parking is available.

Approximately 50 people will take part in the study at the UI. The study involves nearly 160 sites worldwide, and approximately 4,000 individuals are expected to participate.

For more information about the study, call the UI Lipid Research Center toll-free at 800-887-6917 or 319-384-5048.

University of Iowa Health Care describes the partnership between the UI Roy J. and Lucille A. Carver College of Medicine and UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide. Visit UI Health Care online at www.uihealthcare.com.

STORY SOURCE: University of Iowa Health Science Relations, 5137 Westlawn, Iowa City, Iowa 52242-1178

CONTACT:
Interested Study Participants: UI Lipid Research Center, 800-887-6917 or 319-384-5048
Media: Becky Soglin, 319-335-6660, becky-soglin@uiowa.edu