University of Iowa Health Care News Release
June 26, 2003
UI Study On Aging Invites Participants
People ages 55 to 90 who have atherosclerosis (deposits of fatty substances or other material that narrow or block blood vessels) are invited to participate in a University of Iowa Health Care study. The purpose of the study is to better understand how blood vessel function relates to cognition, which is the ability to remember, pay attention, learn and solve problems.
For possible eligibility, volunteers must have at least one of the following conditions: atherosclerosis (blockage of the blood vessels), claudication (peripheral vascular disease), angina, previous heart attack, angioplasty or stent placement. Eligible participants must not have had a stroke or coronary artery bypass surgery.
The study will involve four visits to UI Hospitals and Clinics over the course of three years and phone contact approximately every three months throughout the study. Visits 1 and 2 will take place close together at the start of participants' entry into the study. Visits 3 and 4 will be held three years later, at the end of the study.
Visits 1 and 3 will involve an interview, health history, cognitive testing and physical examination. A small sample of blood will be drawn to measure blood fats, sugars, hormones and proteins. In addition, the blood samples taken at the first visit will be used as part of a DNA analysis to determine whether a particular gene is present that may be a risk factor for some forms of cognitive impairment.
During visits 2 and 4, participants will be given several medications to see how they affect blood vessel function over a three-hour period. In addition, at these visits participants will receive a 30-minute ultrasound (sonar) scan of the arm as another test of blood vessel function.
Compensation is available. Approximately 110 people will take part in
the study, which is led by David Moser, Ph.D., UI assistant professor of
psychiatry. The five-year investigation is funded by a $778,000 grant from
the National Institute on Aging.
University of Iowa Health Care describes the partnership between the UI Roy J. and Lucille A. Carver College of Medicine and UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide. Visit UI Health Care online at http://www.uihealthcare.com.
STORY SOURCE: University of Iowa Health Science Relations, 5137 Westlawn, Iowa City, Iowa 52242-1178
CONTACTS: Media: Becky Soglin (writer), 319-335-6660,email@example.com Study Participants: Becky Reese (UI research assistant in psychiatry), 319-353-4276.