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University of Iowa News Release

July 10, 2003

UI Health Care Physician To Be Honored

A professor of pediatrics who cares for children affected by asthma and allergies at Children's Hospital of Iowa will receive a special honor in October in recognition of his stellar career.

Miles Weinberger, M.D., director of the Pediatric Allergy & Pulmonary Division at University of Iowa Hospitals and Clinics, will accept the 2003 Sumner J. Yaffe LifeTime Achievement Award in Pediatric Pharmacology and Therapeutics Oct. 2 in Dana Point, Calif.

The award is sponsored by Ross Products, a division of Abbott Laboratories, Inc., and is named in honor of Sumner J. Yaffe, M.D., who has committed his medical career to the improvement of children's health through the expansion of the field of pediatric pharmacology and therapeutics. The award consists of a cash prize and a specially struck and inscribed plaque. Weinberger will address a special session during the Pediatric Pharmacy Advocacy Group annual meeting and will publish his lecture in the Journal of Pediatric Pharmacology and Therapeutics.

Weinberger graduated from the University of Pittsburgh. He received his pediatric training at the University of California in San Francisco. He worked two years at the Perinatal Research Branch of the National Institutes of Neurological Disease and Stroke, and also served as a clinical assistant professor of pediatrics at Georgetown University during that time. Weinberger then completed a fellowship in pediatric allergy and pulmonary disease at the National Jewish Hospital and University of Colorado. He spent two years in private practice in Marin County, Calif., during which time he maintained a teaching clinic at the Santa Rosa Family Practice Training Program. He then returned to the University of Colorado where he completed a fellowship in clinical pharmacology.

Weinberger joined the faculty of the UI Department of Pediatrics in 1975 as director of the Pediatric Allergy & Pulmonary Division. Since that time, he has seen the division grow to six faculty members. More than 300 pediatric residents have rotated through the clinical service of the division and 28 subspecialty trainees have graduated from the program with board eligibility in allergy and/or pediatric pulmonology.

Weinberger has authored more than 160 manuscripts, 30 book chapters and monographs, a book titled "Managing Asthma" and several web-based physician and family education publications. He has made more than 300 presentations to his peers throughout the United States and in 19 foreign nations.

Weinberger pioneered the concept of asthma controller medications through his research on maintenance therapy with theophylline alone and in combination with ephedrine. His research demonstrated that the most widely used medication of its time contained an ingredient, ephedrine, which increased side effects without benefit. In 1976, Weinberger published a pivotal paper in the Journal of the American Medical Association titled "Intravenous Aminophylline Dosage: Use of Serum Theophylline Measurements for Guidance." This work ushered in the era of theophylline monitoring for individualization of theophylline dosing and led to the development of a reference range for theophylline. He then went on to conduct studies characterizing the clinical pharmacology of theophylline in children, drug-drug interactions with theophylline and absorption characteristic of various formulations of theophylline.

Weinberger's interests have also included the means to prevent emergency room visits and hospitalizations for asthma. A landmark publication in 1987 demonstrated that exacerbations of asthma in patients otherwise well controlled could be aborted by early intervention with a short course of an oral corticosteroid. He further demonstrated the particular importance of this for the population with the highest rate of hospitalizations, young children with viral respiratory infection induced asthma. A symposium on the treatment of viral respiratory infection induced asthma in young children organized last year by Weinberger was subsequently published under his editorial direction as a supplement to the Journal of Pediatrics.

The Pediatric Pharmacy Advocacy Group is the first established and largest international professional organization of pediatric pharmacists. Its members include practicing pediatric pharmacists, hospital administrators, clinical scientists and other associated health care professional. The organization is committed to improving the lives of children through education, research and advocacy, which promotes the safe and effective use of medication in children.

University of Iowa Health Care describes the partnership between the University of Iowa Roy J. and Lucille A. Carver College of Medicine and UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide. Visit UI Health Care online at http://www.uihealthcare.com.

STORY SOURCE: Joint Office for Planning, Marketing and Communications, 200 Hawkins Drive, Room 8798 JPP, Iowa City, Iowa 52242-1009

CONTACT(S): Tom Moore, 319-356-3945, thomas-moore@uiowa.edu. Writer: Sherry Leudke, Pharm.D., 806-356-4659, sluedtke@cortex.ama.ttuhsc.edu