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University of Iowa News Release

August 4, 2003

People With Schizophrenia Invited To Participate In Memory Study

People with schizophrenia or schizoaffective disorder are invited to participate in a University of Iowa study to determine the safety and effectiveness of a new medication, compared to placebo (inactive substance), in treating cognitive impairment such as thinking and memory problems.

Men and women ages 18 to 55 are eligible if their symptoms have been stable for at least three months and they have not been hospitalized for at least six months. Women must not be pregnant, nursing or planning to get pregnant.

Eligible participants randomly will be assigned to receive either the study drug Aricept or a placebo that looks like Aricept. During the study, participants will continue to take any current antipsychotic medication as prescribed by their doctor.

The study will last approximately 16 weeks and include six visits to the department of psychiatry on the UI campus. The visits will each last three to four hours. The study includes a physical examination and laboratory testing. Compensation may be available.

For more information, contact Tim Holman at 319-335-6769, Jane Kerr at 319-353-4955 or, for toll-free inquiries, UI Health Access at 800-777-8442.

University of Iowa Health Care describes the partnership between the UI Roy J. and Lucille A. Carver College of Medicine and UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide. Visit UI Health Care online at www.uihealthcare.com.

STORY SOURCE: University of Iowa Health Science Relations, 5137 Westlawn, Iowa City, Iowa 52242-1178

CONTACTS:
PROSPECTIVE STUDY PARTICIPANTS: Tim Holman at 319-335-6769, Jane Kerr at 319-353-4955 or, for toll-free inquiries, UI Health Access at 800-777-8442

MEDIA: Becky Soglin, Writer, 319-335-6660