CONTACT: DAVE PEDERSEN
Iowa City IA 52242
(319) 335-8032; fax (319) 384-4638
Release: April 29, 2002
Noted immunology researcher Beutler to give lectures May 1-3
Beutler, M.D., professor of immunology at the Scripps Research Institute in
LaJolla, Calif., will give three lectures at the University of Iowa May 1-3.
Beutler's will lecture on Innate Immune Sensing: A Few Centuries of
Progress at 4 p.m. Wednesday, May 1, in Auditorium III in the Bowen
Science Building. The talk is part of a Pfizer-sponsored Visiting Infectious
Diseases Scholar program in the UI Department of Internal Medicine.
At 1 p.m. Thursday, May 2, Beutler will discuss "Infectious Disease
and the Interface Between Genes and Environment" in Medical Alumni Auditorium,
room E-331 General Hospital in UI Hospitals and Clinics.
At 9 a.m. Friday, May 3, Beutler will present the lecture, "Forward
Genetic Analysis of Host Defense" in the Peterson Conference Room, room
E-140 in UI Hospitals and Clinics.
All three lectures are open to UI faculty, staff and students and the public.
Beutler has made major contributions to the understanding of the responses
of all animals, including humans, to infection. Beginning in 1985 at Rockefeller
University, he and his colleagues made a series of discoveries that revealed
that production and secretion of the protein cachectin/tumor necrosis factor
into body fluids was an important early response to infection and cancer that
could, under unfavorable circumstances, be responsible for many of the worst
outcomes of these illnesses, including death.
More recently, his laboratory has played a major role in the discovery of
a host cell receptor that is essential in permitting very sensitive responses
to invading bacteria. This work was done at the University of Texas Southwestern
Medical Center in Dallas and at the Scripps Research Institute, where Beutler
hold his current position.
Beutler's research has helped provide a general scheme in which to better
understand infection, cancer and other diseases in which inflammation is important.
His observations and concepts also have spawned interest in diversity within
specific human genes that may help explain genetic dispositions to infection
and a variety of other inflammatory diseases.
University of Iowa Health Care describes the partnership between
the UI Roy J. and Lucille A. Carver College of Medicine and UI Hospitals and
Clinics and the patient care, medical education and research programs and
services they provide. Visit UI Health Care online at www.uihealthcare.com.