WRITER: CLANCY CHAMPANOIS
CONTACT: TOM MOORE
Joint Office for Planning, Marketing and Communications
8788 John Pappajohn Pavilion
Iowa City IA 52242
Release: Aug. 3, 2001
UI invites people to participate in study of new endovascular surgical
IOWA CITY, Iowa -- University of Iowa Health Care researchers led by John
Chaloupka, M.D., UI associate professor of radiology and director of the Division
of Interventional Neuroradiology, invite people who have an aneurysm of a
brain artery to participate in a research study. This study will evaluate
whether a new endovascular surgical device, known as Onyx, is a good alternative
to platinum coil devices for the treatment of aneurysms within the brain.
The Onyx device is a liquid polymer (ethylene vinyl co-polymer) that upon
contact with blood becomes solid and rubbery. The Onyx will be used to fill
up an aneurysm and, upon becoming solid, will prevent blood from flowing into
the aneurysm, therefore preventing the aneurysm from rupturing.
Currently, endovascular surgical treatment of brain aneurysms is accomplished
with detachable platinum coil devices that are used to fill up the space within
the aneurysm. These coil-type devices are approved by the U.S. Food and Drug
Administration (FDA). However, the Onyx embolization device is currently not
FDA-approved and therefore is considered investigational. The Oynx device
has been used successfully in almost 90 people with aneurysms in Europe and
Asia, with no complications that can be directly related to the device.
Ideal participants in this research study are those patients who have an
aneurysm of a brain artery. Participation will require a commitment of a minimum
of six months, which consists of the initial operation, a one-month follow-up
clinic visit and CT scan, and a six-month follow-up angiogram and MRI scan.
For more information, referring physicians and interested individuals can
contact Chaloupka at (319) 356-4329 or Jeri Sieren, research assistant in
radiology, at (319) 356-7969.
University of Iowa Health Care describes the partnership between
the UI College of Medicine and the UI Hospitals and Clinics and the patient
care, medical education and research programs and services they provide. Visit
UI Health Care online at www.uihealthcare.com.