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CONTACT: BECKY SOGLIN
2130 Medical Laboratories
Iowa City IA 52242
(319) 335-6660; fax (319) 335-9917
e-mail:becky-soglin@uiowa.edu

Release: May 18, 1999

Participants invited to take part in UI study on chronic heart failure

IOWA CITY, Iowa -- University of Iowa cardiologists are conducting a clinical study on how an injected protein inhibitor may improve the health of people with chronic heart failure.

Men and women ages 18 to 85 with decreased left ventricular systolic dysfunction are invited to participate in the study. To participate, women may not be pregnant.

Participants will need to take injections three times a week and make weekly visits to the UI for the first month, then monthly visits for a minimum of five additional months. For more information, call Page Scovel, staff nurse, at (319) 384-8005.

William G. Cotts, M.D., UI assistant professor of internal medicine and lead investigator, said the study will examine whether the injections can diminish or prevent the negative effects of a certain protein often found in elevated amounts in the blood of people with heart failure.

"We'll be looking at whether the inhibitor reduces symptoms such as fatigue and shortness of breath, and whether it can help people with heart failure live longer," Cotts said.

The UI is one of several centers nationwide participating in the study.