CONTACT: JENNIFER CRONIN
2130 Medical Laboratories
Iowa City IA 52242
(319) 335-5661; fax (319) 335-9917
Release: April 6, 1999
UI department of anatomy and cell biology researchers
receive research grants
IOWA CITY, Iowa -- Three University of Iowa researchers
in the College of Medicine's department of anatomy and cell biology recently
received grants for their work.
Robin L. Davisson, Ph.D., assistant professor of anatomy
and cell biology, received a Carver Medical Research Initiative Grant for
her project titled "Brain site-selective gene deletion as a tool for understanding
central control of cardiovascular function."
Davisson's grant is for $30,000 and runs from April 1,
1999 to March 31, 2000.
Davisson's work will focus on inducing gene knockout in
selective sites in the brain.
Dawn A. Kirschmann, Ph.D., assistant research scientist
in anatomy and cell biology, received the Florence Lindsay Young Investigator
Award for her project titled "Role of lysyl oxidase in breast cancer metastasis."
Lysyl oxidase, an enzyme that functions in the nucleus
as well as outside of cells, is abundantly present in breast cancer cells
that have a highly invasive and metastatic phenotype. This project begins
to assess the involvement of lysyl oxidase in promoting breast cancer cell
invasion and metastasis. This award is for $14,700 and runs from March 1,
1999 to Feb. 28, 2000.
Jeanne M. Snyder, Ph.D., professor of anatomy and cell
biology, will receive $996,100 from the National Institutes of Health for
her four-year project "Retinoic acid receptors and alveoli formation." Currently,
there is no way to repair alveoli destruction in the lungs from emphysema.
Snyder and her co-investigator, Steven McGowan, M.D., associate professor
of internal medicine, are studying whether retinoic acid, a metabolite of
vitamin A, will cause alveoli to reform.
Snyder's grant started April 1.